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If you are a woman able to have a baby, you must not take Epilim unless you use an effective method of birth control (contraception) at all times during your entire treatment with Epilim. Before you install the update we recommend that you submit any PCT/RO/101 drafts you have already prepared. R. Burt, Report of the On-line Communications Committee (OCC) [ permanent dead link], epi Information 2/2008, p. 59. [ dead link]

PCT-SFD plug-in − update for enabling submissions to the EPO (and Lithuanian Patent Office), and the filing of additional document types and various corrections, available for (OLF) V5.07 (build 5.0.7.118) When a divisional application is filed by reference to an international application it is now possible to enter the data for the international application in the "Reference" tab Use the discussion forum and get all the latest news and views about our online products. Read the regular postings from the forum team, post your questions, and answer those of other users.EP (Iceland) and cryptovision update August 2019 available for (OLF) V5.11 (build 5.0.11.175 or lower) Ask your doctor about taking folic acid when planning to have a baby. Folic acid can lower the general risk of spina bifida and early miscarriage that exists with all pregnancies. However, it is unlikely that it will reduce the risk of birth defects associated with valproate use. patch contains updates to the GB forms with chanes to supply of paper citations coming into force 8 March 2020. There is the possibility that a Divisional application may itself give rise to a further Divisional. (see S.15(9)). Should this occur, the time period is extended in the same manner as outlined above. Although the pharmacokinetics of valproate are modified in the elderly, they have limited clinical significance and dosage should be determined by seizure control. The volume of distribution is increased in the elderly and because of decreased binding to serum albumin, the proportion of free drug is increased. This will affect the clinical interpretation of plasma valproic acid levels.

Skin rash or skin lesions with a pink/red ring and a pale centre which may be itchy, scaly or filled with fluid. The rash may appear especially on the palms or soles of your feet. These may be signs of a condition named ‘erythema multiforme’.F1001, F1038: Amendment of Rule 19 EPC: removal of the option for inventors to waive their right to be notified; see OJ EPO 2021, A12 Like all medicines, sodium valproate can cause side effects, although not everyone gets them. Common side effects

The r.19 period is extendable by a discretionary extension under r.108(1). The extension is however subject to restriction under r.108(5) and r.108(7), (see 10.31) as it is listed in Part 3 of Schedule 4 to the Patents Rules 2007. The extension (or any further extension) is restricted to 2 months only. Any such request should be made in writing and referred to the Deputy Director/Examiner. There is no fee or Form 52 required. long-lasting and severe nausea, vomiting or stomach pain – these may be signs of acute pancreatitis (an inflamed pancreas) PCT (PCT/RO/101 update January 2019) update 20 March 2019 available for (OLF) V5.11 (build 5.0.11.172 or lower) This patch contains updates to the GB forms: Information on the sharing of the results of searches and examinations with other patent offices, mandatory supply of deposit account details if paying by your deposit account and mandatory supply of PDAS access code if obtaining priority documents from PDAS. EP (minor technical corrections) update 8 January 2020 available for (OLF) V5.11 (build 5.11.175 or lower)

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EP (minor functional changes) and PCT (fee update, automatic debiting PCTDEMAND and PCTSFD) update 1 April 2015 available for (OLF) V5.08 (build 5.08.132 or higher) This patch contains updated certificates which are required for filings to the UK IPO from 17 October 2015. Our average delivery takes between 5 to 12 business days. However, even in the best circumstances, delays can happen outside our control, especially with Covid-19. PCT (PCT/RO/101 update July 2020) update 25 August 2020 available for (OLF) V5.12 (build 5.0.12.176) The PDF request is generated and displayed when an international application is generated from a template.